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It thrives in extremely high temperatures, and takes years to mature. The San Bushmen of the Kalahari, one of the world's oldest and most primitive tribes, had been eating the Hoodia for thousands of years, to stave off hunger during long hunting trips. When South African scientists were routinely testing it, they discovered the plant contained a previously unknown molecule, which has since been christened P 57. P 57 affects a part of your brain, the hypothalamus. Within that mid-brain there are nerve cells that sense glucose sugar. When you eat, blood sugar goes up because of the food, these cells start firing and now you are full. What the Hoodia seems to contain is a molecule that is about 10,000 times as active as glucose. It goes to the mid-brain and actually makes those nerve cells fire as if you were full. But you have not eaten. Nor do you want to. When the first animal trials for Hoodia were performed on rats, a species that will eat literally anything, they stopped eating completely. When the first human clinical trial was conducted, a morbidly obese group of people were placed in a "phase 1 unit", a place as close to prison as it gets. All the volunteers could do all day was read papers, watch television, and eat. Half were given Hoodia, half placebo. Fifteen days later, the Hoodia group had reduced their calorie intake by 1000 a day. It's hard to diet when you're hungry. Your body is telling you to eat, so you eat. This is the single biggest factor that keeps people from loosing weight. No matter how strong your will power is, you eventually break down and start eating too much again. Hoodia tackles every weight problem by the root: it simply stops your craving for food. Do you think you could loose weight if you ate 50% less then you do now? You bet you could. 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